Reversing the discovery paradigm: A new approach to the combinatorial discovery of fluorescent chemosensors

被引：130

作者：

Mello, JV ^{[1
]}

Finney, NS ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 29期

关键词：

D O I：

10.1021/ja043682p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report here a new approach to the discovery of fluorescent chemosensors in which a new signaling mechanism allows a core fluorophore to be used in a combinatorial search for new binding events, thus reversing the reigning discovery paradigm. Copyright © 2005 American Chemical Society.

引用

页码：10124 / 10125

页数：2

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