Validation tools: can they indicate the information content of macromolecular crystal structures?

被引:17
作者
Dodson, EJ [1 ]
Davies, GJ
Lamzin, VS
Murshudov, GN
Wilson, KS
机构
[1] Univ York, York YO1 5DD, N Yorkshire, England
[2] EMBL Hamburg Outstn, D-22603 Hamburg, Germany
[3] CLRC, Daresbury Lab, Warrington WA4 4AD, Cheshire, England
来源
STRUCTURE WITH FOLDING & DESIGN | 1998年 / 6卷 / 06期
基金
英国生物技术与生命科学研究理事会; 英国医学研究理事会;
关键词
D O I
10.1016/S0969-2126(98)00070-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The explosive increase in the number of published three-dimensional structures of macromolecules determined by X-ray analysis places a responsibility on experimentalists, referees and curators of databases to ensure correspondence between the structure parameters and data. Validation tools will evolve as more appropriate statistical techniques and new information, such as that from proteins analysed at atomic resolution, becomes available.
引用
收藏
页码:685 / 690
页数:6
相关论文
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[31]  
Wilson KS, 1998, J MOL BIOL, V276, P417