Identification of potent and novel small-molecule inhibitors of caspase-3

被引:23
作者
Allen, DA [1 ]
Pham, P [1 ]
Choong, IC [1 ]
Fahr, B [1 ]
Burdett, MT [1 ]
Lew, W [1 ]
DeLano, WL [1 ]
Gordon, EM [1 ]
Lam, JW [1 ]
O'Brien, T [1 ]
Lee, D [1 ]
机构
[1] Sunesis Pharmaceut Inc, San Francisco, CA 94080 USA
关键词
D O I
10.1016/j.bmcl.2003.08.024
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The design and synthesis of a series of novel, reversible, small molecule inhibitors of caspase-3 are described. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3651 / 3655
页数:5
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