Principles for the post-GWAS functional characterization of cancer risk loci

被引：333

作者：

Freedman, Matthew L. ^{[2
,3
]}

Monteiro, Alvaro N. A. ^{[4
]}

Gayther, Simon A. ^{[5
,6
]}

Coetzee, Gerhard A. ^{[7
]}

Risch, Angela ^{[8
]}

Plass, Christoph ^{[8
]}

Casey, Graham ^{[9
]}

De Biasi, Mariella ^{[10
]}

Carlson, Chris ^{[11
]}

Duggan, David ^{[12
]}

James, Michael ^{[13
]}

Liu, Pengyuan ^{[13
]}

Tichelaar, Jay W. ^{[13
]}

Vikis, Haris G. ^{[13
]}

You, Ming ^{[13
]}

Mills, Ian G. ^{[1
,14
]}

机构：

[1] Univ Oslo, Nord European Mol Biol Lab EMBL Partnership, Norwegian Ctr Mol Med, Oslo, Norway

[2] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA

[3] Eli & Edythe L Broad Inst MIT & Harvard, Cambridge, MA USA

[4] Univ S Florida, Coll Med, H Lee Moffitt Canc Ctr & Res Inst, Canc Epidemiol Program, Tampa, FL 33612 USA

[5] Univ So Calif, Keck Sch Med, Los Angeles, CA 90033 USA

[6] UCL, Elizabeth Garrett Anderson Inst Womens Hlth EGA, Translat Res Lab, London, England

[7] Univ So Calif, Dept Urol, Norris Canc Ctr, Los Angeles, CA USA

[8] German Canc Res Ctr, Div Epigenom & Canc Risk Factors, D-6900 Heidelberg, Germany

[9] Univ So Calif, Dept Prevent Med, Los Angeles, CA 90089 USA

[10] Baylor Coll Med, Dept Neurosci, Houston, TX 77030 USA

[11] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA

[12] Translat Genom Res Inst TGen, Phoenix, AZ USA

[13] Med Coll Wisconsin, Milwaukee, WI 53226 USA

[14] Canc Res UK Cambridge Res Inst, Urooncol Res Grp, Cambridge, England

来源：

NATURE GENETICS | 2011年 / 43卷 / 06期

关键词：

GENOME-WIDE ASSOCIATION; LONG-RANGE INTERACTION; HUMAN GENE-EXPRESSION; GERMLINE EPIMUTATION; VARIANTS; BREAST; IDENTIFICATION; EPIGENOMICS; ELEMENTS; UNDERLIE;

D O I：

10.1038/ng.840

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

[No abstract available]

引用

页码：513 / 518

页数：6

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