Downstream factors in transforming growth factor-β family signaling

被引：29

作者：

Visser, JA ^{[1
]}

Themmen, APN ^{[1
]}

机构：

[1] Erasmus Univ, Fac Med & Hlth Sci, Dept Endocrinol & Reprod, NL-3000 DR Rotterdam, Netherlands

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 1998年 / 146卷 / 1-2期

关键词：

Smad proteins; G proteins; TGF-beta family members;

D O I：

10.1016/S0303-7207(98)00198-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The recently identified family of Smad proteins has given insight in the understanding of how members of the transforming growth factor-beta (TGF-beta) family relay their signal to the nucleus. Besides Smad proteins, G proteins and MAPKs are also involved in the downstream signaling of TGF-beta family members. The identification of elements that function downstream in the TGF-beta signaling pathway and the fact that these downstream players can interact with the signaling cascade of other growth factors, may give insight into the diverse biological responses evoked by the TGF-beta family members. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：7 / 17

页数：11

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