Integrin associated proteins

被引:310
作者
Hemler, ME [1 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
D O I
10.1016/S0955-0674(98)80032-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Integrin cytoplasmic domains may interact directly with serveral different cytoskeletal proteins and intracellular signaling molecules. Also, integrins interact directly with other transmembrane structures, including transmembrane-4 superfamily (TM4SF) proteins. New evidence suggests that TM4SF proteins may act as linkers between extracellular integrin a chain domains and intracellular signaling molecules, such as phosphatidylinositol 4-kinase and protein kinase C.
引用
收藏
页码:578 / 585
页数:8
相关论文
共 86 条
  • [41] Decreased resistance to bacterial infection and granulocyte defects in IAP-deficient mice
    Lindberg, FP
    Bullard, DC
    Caver, TE
    Gresham, HD
    Beaudet, AL
    Brown, EJ
    [J]. SCIENCE, 1996, 274 (5288) : 795 - 798
  • [42] MOLECULAR-CLONING OF INTEGRIN-ASSOCIATED PROTEIN - AN IMMUNOGLOBULIN FAMILY MEMBER WITH MULTIPLE MEMBRANE-SPANNING DOMAINS IMPLICATED IN ALPHA-NU-BETA-3-DEPENDENT LIGAND-BINDING
    LINDBERG, FP
    GRESHAM, HD
    SCHWARZ, E
    BROWN, EJ
    [J]. JOURNAL OF CELL BIOLOGY, 1993, 123 (02) : 485 - 496
  • [43] MEMBRANE COFACTOR PROTEIN (MCP OR CD46) - NEWEST MEMBER OF THE REGULATORS OF COMPLEMENT ACTIVATION GENE-CLUSTER
    LISZEWSKI, MK
    POST, TW
    ATKINSON, JP
    [J]. ANNUAL REVIEW OF IMMUNOLOGY, 1991, 9 : 431 - 455
  • [44] Lu CF, 1997, J IMMUNOL, V159, P268
  • [45] Integrin-mediated activation of focal adhesion kinase is independent of focal adhesion formation or integrin activation - Studies with activated and inhibitory beta(3) cytoplasmic domain mutants
    Lyman, S
    Gilmore, A
    Burridge, K
    Gidwitz, S
    White, GC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (36) : 22538 - 22547
  • [46] The tetraspanin superfamily: Molecular facilitators
    Maecker, HT
    Todd, SC
    Levy, S
    [J]. FASEB JOURNAL, 1997, 11 (06) : 428 - 442
  • [47] Mannion BA, 1996, J IMMUNOL, V157, P2039
  • [48] INTEGRIN FUNCTION - MOLECULAR HIERARCHIES OF CYTOSKELETAL AND SIGNALING MOLECULES
    MIYAMOTO, S
    TERAMOTO, H
    COSO, OA
    GUTKIND, JS
    BURBELO, PD
    AKIYAMA, SK
    YAMADA, KM
    [J]. JOURNAL OF CELL BIOLOGY, 1995, 131 (03) : 791 - 805
  • [49] Phosphoinositide 3-OH kinase activates the β2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1
    Nagel, W
    Zeitlmann, L
    Schilcher, P
    Geiger, C
    Kolanus, J
    Kolanus, W
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (24) : 14853 - 14861
  • [50] Identification of a novel calcium-binding protein that interacts with the integrin alpha(IIb) cytoplasmic domain
    Naik, UP
    Patel, PM
    Parise, LV
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (08) : 4651 - 4654