Cytogenetic classification of renal cell cancer

被引：54

作者：

vandenBerg, E

Dijkhuizen, T

Oosterhuis, JW

vanKessel, AG

deJong, B

Storkel, S

机构：

[1] UNIV WITTEN HERDECKE,WUPPERTAL CLIN GMBH,INST PATHOL,WUPPERTAL,GERMANY

[2] UNIV NIJMEGEN,DEPT MED GENET,NIJMEGEN,NETHERLANDS

[3] UNIV NIJMEGEN,DEPT HUMAN GENET,NIJMEGEN,NETHERLANDS

[4] ACAD HOSP,DR DANIEL DEN HOED CANC CTR,EXPT ONCOL LAB,ROTTERDAM,NETHERLANDS

来源：

CANCER GENETICS AND CYTOGENETICS | 1997年 / 95卷 / 01期

关键词：

D O I：

10.1016/S0165-4608(96)00289-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic and molecular genetic investigations in cancer are important fools to address problems of oncogenesis and tumor progression, of classification, and of diagnosis of rumors. A combination of advanced molecular genetic, cytogenetic, and (immune) histopathologic analysis will contribute significantly to the elucidation of the oncogenic steps that lead to immortalization and subsequent malignant behavior. In this review written on the occasion of Dr. Avery Sandberg's 75th anniversary, we will present a model for the pathogenesis of renal cell tumors based on a new cytomorphologic classification and our (cyto)genetic analysis of about 175 renal cell tumors, together with the accumulated data in the literature. (C) Elsevier Science Inc., 1997.

引用

页码：103 / 107

页数：5