Quantitative analysis by microchip capillary electrophoresis -: current limitations and problem-solving strategies

被引：35

作者：

Revermann, Tobias ^{[1
,2
,3
]}

Goetz, Sebastian ^{[1
,2
]}

Kuennemeyer, Jens ^{[3
]}

Karst, Uwe ^{[1
,2
,3
]}

机构：

[1] Univ Twente, Inst Nanotechnol, Chem Anal Grp, NL-7500 AE Enschede, Netherlands

[2] Univ Twente, Inst Nanotechnol, MESA, NL-7500 AE Enschede, Netherlands

[3] Univ Munster, Inst Anorgan & Analyt Chem, D-48149 Munster, Germany

来源：

ANALYST | 2008年 / 133卷 / 02期

关键词：

D O I：

10.1039/b711165g

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Obstacles and possible solutions for the application of microchip capillary electrophoresis in quantitative analysis are described and critically discussed. Differences between the phenomena occurring during conventional capillary electrophoresis and microchip-based capillary electrophoresis are pointed out, with particular focus on electrolysis, bubble formation, clogging, surface interactions, injection and aspects related to the power supply. Current drawbacks are specified and improvements for successful quantitative microchip capillary electrophoresis are suggested.

引用

页码：167 / 174

页数：8

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