Tirucalla-5,24-dien-3 beta-ol [(13 alpha,14 beta,17 alpha,20S)-lanosta-5,24-dien-3 beta-ol] and three other Delta(5)-unsaturated tirucallanes from the roots of Bryonia dioica Jacq: The first naturally occurring C-10 methylated tetracyclic triterpene alcohols with a Delta(5)-monounsaturated skeleton

被引：29

作者：

Akihisa, T

Kimura, Y

Kokke, WCMC

Takase, SI

Yasukawa, K

Tamura, T

机构：

[1] NIHON UNIV,COLL PHARM,FUNABASHI,CHIBA 274,JAPAN

[2] ZYNAXIS INC,MALVERN,PA 19355

[3] TOHO UNIV,COLL SCI & TECHNOL,FUNABASHI,CHIBA 274,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 19期

关键词：

D O I：

10.1039/p19960002379

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four novel triterpene alcohols with a Delta(5)-unsaturated tirucallane-type skeleton, i.e. tirucall-5-en-3 beta-ol, tirucalla-5,24-dien-3 beta-ol, 24-methyltirucalla-5,24(24(1))-dien-3 beta-ol and (24S)-24-methyltirucalla-5,25-dien-3 beta-ol, have been isolated from the roots of Bryonia dioica Jacq. (Cucurbitaceae). The structures have been determined by spectroscopic and chromatographic methods. These compounds are the first examples of naturally occurring C-10 methylated triterpenes with a Delta 5-monounsaturated skeleton.

引用

页码：2379 / 2384

页数：6

共 39 条

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