GOChase: correcting errors from Gene Ontology-based annotations for gene products

被引:10
作者
Park, YR
Park, CH
Kim, JH [1 ]
机构
[1] Seoul Natl Univ, Coll Med, SNUBI, Seoul 110799, South Korea
[2] Seoul Natl Univ, Coll Med, Human Genome Res Inst, Seoul 110799, South Korea
关键词
D O I
10.1093/bioinformatics/bti106
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The Gene Ontology (GO) is a controlled biological vocabulary that provides three structured networks of terms to describe biological processes, cellular components and molecular functions. Many databases of gene products are annotated using the GO vocabularies. We found that some GO-updating operations are not easily traceable by the current biological databases and GO browsers. Consequently, numerous annotation errors arise and are propagated throughout biological databases and GO-based high-level analyses. GOChase is a set of web-based utilities to detect and correct the errors in GO-based annotations.
引用
收藏
页码:829 / 831
页数:3
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