A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles

被引：104

作者：

Dobbs, AP

Guesné, SJJ

Martinovic, S

Coles, SJ

Hursthouse, MB

机构：

[1] Univ Exeter, Sch Chem, Exeter EX4 4QD, Devon, England

[2] Univ Southampton, Dept Chem, EPSRC Natl Crystallog Serv, Southampton SO17 1BJ, Hants, England

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 20期

关键词：

D O I：

10.1021/jo034981k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A versatile and high-yielding indium trichloride mediated cyclization reaction of silylated homoallylic alcohols, thiols, or amines with aldehydes or epoxides is described as a rapid route to a range of unsaturated heterocycles. The excellent diastereoselectivity observed offers a method of wide scope and generality.

引用

页码：7880 / 7883

页数：4

共 22 条

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