Metabolomics and Surgical Oncology: Potential Role for Small Molecule Biomarkers

被引：60

作者：

Davis, Vanessa W. ^{[1
]}

Bathe, Oliver F. ^{[2
]}

Schiller, Daniel E. ^{[1
]}

Slupsky, Carolyn M. ^{[3
,4
]}

Sawyer, Michael B. ^{[5
]}

机构：

[1] Univ Alberta, Dept Surg, Edmonton, AB, Canada

[2] Univ Calgary, Dept Surg & Oncol, Calgary, AB, Canada

[3] Univ Calif Davis, Dept Nutr, Davis, CA 95616 USA

[4] Univ Calif Davis, Dept Food Sci & Technol, Davis, CA 95616 USA

[5] Univ Alberta, Dept Oncol, Edmonton, AB, Canada

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2011年 / 103卷 / 05期

关键词：

screening and diagnosis; personalized cancer care; tumorigenesis; MAGNETIC-RESONANCE-SPECTROSCOPY; H-1 MR SPECTROSCOPY; GASTROINTESTINAL STROMAL TUMORS; HUMAN COLORECTAL-CANCER; ADVANCED BREAST-CANCER; NMR-BASED METABOLOMICS; MASS-SPECTROMETRY; NEOADJUVANT CHEMOTHERAPY; PROSTATE-CANCER; CELL CARCINOMA;

D O I：

10.1002/jso.21831

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Metabolomics, the newest of the "omics" sciences, has brought much excitement to the field of oncology as a potential new translational tool capable of bringing the molecular world of cancer care to the bedside. While still early in its development, metabolomics could alter the scope and role of surgery in the multidisciplinary treatment of cancer. This review examines potential roles of metabolomics in areas of early cancer detection, personalized therapeutics and tumorigenesis J. Surg. Oncol. 2011; 103: 451-459. (C) 2010 Wiley-Liss, Inc.

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收藏

页码：451 / 459

页数：9

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