Non-invasive functional mapping with multi-channel near infra-red spectroscopic topography in humans

被引：163

作者：

Watanabe, E ^{[1
]}

Yamashita, Y ^{[1
]}

Maki, A ^{[1
]}

Ito, Y ^{[1
]}

Koizumi, H ^{[1
]}

机构：

[1] HITACHI LTD,CENT RES LAB,MED SYST RES DEPT,KOKUBUNJI,TOKYO 185,JAPAN

来源：

NEUROSCIENCE LETTERS | 1996年 / 205卷 / 01期

关键词：

near infra-red spectroscopy; functional mapping; motor cortex; human; hemoglobin; cerebral blood volume;

D O I：

10.1016/0304-3940(96)12376-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Near-infrared spectroscopy (NIRS) is a new technique for non-invasive monitoring of tissue oxygenation and its kinetics. Up to this date, it has been used solely in research for the global hemodynamic change of the brain and for rough regional activation after stimulating the brain physiologically. This paper describes functional, brain mapping using multi channel (ten channel) NIRS by applying the motor stimulation in humans. Our results demonstrate that the regional hemodynamic change was detected in a small area around the motor cortex with a time resolution of 1-2 s. NTRS technique offers considerable potential for research and clinical applications with no invasion.

引用

页码：41 / 44

页数：4

共 17 条

[1] FUNCTIONAL MAPPING OF THE HUMAN VISUAL-CORTEX BY MAGNETIC-RESONANCE-IMAGING [J].

BELLIVEAU, JW ;

KENNEDY, DN ;

MCKINSTRY, RC ;

BUCHBINDER, BR ;

WEISSKOFF, RM ;

COHEN, MS ;

VEVEA, JM ;

BRADY, TJ ;

ROSEN, BR .

SCIENCE, 1991, 254 (5032) :716-719

[2] COGNITION-ACTIVATED LOW-FREQUENCY MODULATION OF LIGHT-ABSORPTION IN HUMAN BRAIN [J].

CHANCE, B ;

ZHUANG, Z ;

UNAH, C ;

ALTER, C ;

LIPTON, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (08) :3770-3774

[3]

COPE M, 1988, MED BIOL ENG COMPUT, V32, P1457

[4] DYNAMIC MULTICHANNEL NEAR-INFRARED OPTICAL IMAGING OF HUMAN BRAIN ACTIVITY [J].

HOSHI, Y ;

TAMURA, M .

JOURNAL OF APPLIED PHYSIOLOGY, 1993, 75 (04) :1842-1846

[5]

LEININGERFOLLER.E, 1979, PFLUEGERS ARCH, V380, P85

[6]

MAKI A, 1995, IN PRESS MED PHYSICS

[7] INTRACEREBRAL PENETRATION OF INFRARED LIGHT [J].

MCCORMICK, PW ;

STEWART, M ;

LEWIS, G ;

DUJOVNY, M ;

AUSMAN, JI .

JOURNAL OF NEUROSURGERY, 1992, 76 (02) :315-318

[8]

NAKAJIMA T, 1994, P SOC MAGNETIC RESON, P687

[9]

NGAI AC, 1988, AM J PHYSIOL, V254, P133

[10]

OBRIG H, 1994, P SOC MAGNETIC RESON, P67

← 1 2 →