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Curing metastatic cancer:: Lessons from testicular germ-cell tumours

被引：175
作者：
Masters, JRW
Köberle, B
机构：
[1] UCL, Inst Urol, Prostate Canc Res Ctr, London W1W 7EJ, England
[2] Univ Pittsburgh, Inst Canc, Hillman Canc Ctr, Pittsburgh, PA 15213 USA
来源：
NATURE REVIEWS CANCER | 2003年 / 3卷 / 07期
关键词：
D O I：
10.1038/nrc1120
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Most metastatic cancers are fatal. More than 80% of patients with metastatic testicular germ-cell tumours (TGCTs), however, can be cured using cisplatin-based combination chemotherapy. Why are TGCTs more sensitive to chemotherapeutics than most other tumour types? Answers to this question could lead to new treatments for metastatic cancers.
引用
收藏
页码：517 / 525
页数：9
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