LSD1 and pluripotency A new player in the network

被引:19
作者
Adamo, Antonio [1 ]
Barrero, Maria J. [1 ]
Izpisua Belmonte, Juan Carlos [1 ,2 ]
机构
[1] Ctr Regenerat Med, Barcelona, Spain
[2] Salk Inst Biol Studies, La Jolla, CA 92037 USA
关键词
EMBRYONIC STEM-CELLS; TRANSCRIPTIONAL REPRESSION; DEVELOPMENTAL REGULATORS; DEMETHYLASE; POLYCOMB; COMPLEXES;
D O I
10.4161/cc.10.19.17052
中图分类号
Q2 [细胞生物学];
学科分类号
071013 [干细胞生物学];
摘要
[No abstract available]
引用
收藏
页码:3215 / 3216
页数:2
相关论文
共 11 条
[1]
LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells [J].
Adamo, Antonio ;
Sese, Borja ;
Boue, Stephanie ;
Castano, Julio ;
Paramonov, Ida ;
Barrero, Maria J. ;
Izpisua Belmonte, Juan Carlos .
NATURE CELL BIOLOGY, 2011, 13 (06) :652-U265
[2]
A bivalent chromatin structure marks key developmental genes in embryonic stem cells [J].
Bernstein, BE ;
Mikkelsen, TS ;
Xie, XH ;
Kamal, M ;
Huebert, DJ ;
Cuff, J ;
Fry, B ;
Meissner, A ;
Wernig, M ;
Plath, K ;
Jaenisch, R ;
Wagschal, A ;
Feil, R ;
Schreiber, SL ;
Lander, ES .
CELL, 2006, 125 (02) :315-326
[3]
Polycomb complexes repress developmental regulators in murine embryonic stem cells [J].
Boyer, LA ;
Plath, K ;
Zeitlinger, J ;
Brambrink, T ;
Medeiros, LA ;
Lee, TI ;
Levine, SS ;
Wernig, M ;
Tajonar, A ;
Ray, MK ;
Bell, GW ;
Otte, AP ;
Vidal, M ;
Gifford, DK ;
Young, RA ;
Jaenisch, R .
NATURE, 2006, 441 (7091) :349-353
[4]
Core transcriptional regulatory circuitry in human embryonic stem cells [J].
Boyer, LA ;
Lee, TI ;
Cole, MF ;
Johnstone, SE ;
Levine, SS ;
Zucker, JR ;
Guenther, MG ;
Kumar, RM ;
Murray, HL ;
Jenner, RG ;
Gifford, DK ;
Melton, DA ;
Jaenisch, R ;
Young, RA .
CELL, 2005, 122 (06) :947-956
[5]
Lysine-Specific Demethylase 1 Regulates the Embryonic Transcriptome and CoREST Stability [J].
Foster, Charles T. ;
Dovey, Oliver M. ;
Lezina, Larissa ;
Luo, Jin Li ;
Gant, Timothy W. ;
Barlev, Nick ;
Bradley, Allan ;
Cowley, Shaun M. .
MOLECULAR AND CELLULAR BIOLOGY, 2010, 30 (20) :4851-4863
[6]
Control of developmental regulator's by polycomb in human embryonic stem cells [J].
Lee, TI ;
Jenner, RG ;
Boyer, LA ;
Guenther, MG ;
Levine, SS ;
Kumar, RM ;
Chevalier, B ;
Johnstone, SE ;
Cole, MF ;
Isono, K ;
Koseki, H ;
Fuchikami, T ;
Abe, K ;
Murray, HL ;
Zucker, JP ;
Yuan, BB ;
Bell, GW ;
Herbolsheimer, E ;
Hannett, NM ;
Sun, KM ;
Odom, DT ;
Otte, AP ;
Volkert, TL ;
Bartel, DP ;
Melton, DA ;
Gifford, DK ;
Jaenisch, R ;
Young, RA .
CELL, 2006, 125 (02) :301-313
[7]
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells [J].
Liang, Jiancong ;
Wan, Ma ;
Zhang, Yi ;
Gu, Peili ;
Xin, Huawei ;
Jung, Sung Yun ;
Qin, Jun ;
Wong, Jiemin ;
Cooney, Austin J. ;
Liu, Dan ;
Zhou Songyang .
NATURE CELL BIOLOGY, 2008, 10 (06) :731-739
[8]
Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A [J].
Macfarlan, Todd S. ;
Gifford, Wesley D. ;
Agarwal, Saurabh ;
Driscoll, Shawn ;
Lettieri, Karen ;
Wang, Jianxun ;
Andrews, Shane E. ;
Franco, Laura ;
Rosenfeld, Michael G. ;
Ren, Bing ;
Pfaff, Samuel L. .
GENES & DEVELOPMENT, 2011, 25 (06) :594-607
[9]
Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2 [J].
Pasini, Diego ;
Hansen, Klaus H. ;
Christensen, Jesper ;
Agger, Karl ;
Cloos, Paul A. C. ;
Helin, Kristian .
GENES & DEVELOPMENT, 2008, 22 (10) :1345-1355
[10]
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation [J].
Wang, Jing ;
Hevi, Sarah ;
Kurash, Julia K. ;
Lei, Hong ;
Gay, Frederique ;
Bajko, Jeffrey ;
Su, Hui ;
Sun, Weitao ;
Chang, Hua ;
Xu, Guoliang ;
Gaudet, Francois ;
Li, En ;
Chen, Taiping .
NATURE GENETICS, 2009, 41 (01) :125-129