Convergent protein synthesis

被引:24
作者
Casi, G [1 ]
Hilvert, D [1 ]
机构
[1] ETH Honggerberg, Swiss Fed Inst Technol, Organ Chem Lab, CH-8093 Zurich, Switzerland
关键词
D O I
10.1016/j.sbi.2003.09.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Methods for the chemical synthesis of proteins have advanced considerably over the past decade. In many instances, laboratory synthesis can now be considered a viable alternative to ribosomal biosynthesis, especially when custom modifications of a protein are desired; chemical approaches guarantee virtually unlimited and tunable variation of the covalent structure of a polypeptide.
引用
收藏
页码:589 / 594
页数:6
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