Modeling coincidence detection in nucleus laminaris

被引：38

作者：

Grau-Serrat, V

Carr, CE

Simon, JZ ^{[1
]}

机构：

[1] Univ Maryland, Dept Elect & Comp Engn, College Pk, MD 20742 USA

[2] Univ Maryland, Dept Biol, College Pk, MD 20742 USA

[3] Univ Maryland, Syst Res Inst, College Pk, MD 20742 USA

[4] Univ Maryland, Program Neurosci & Cognit Sci, College Pk, MD 20742 USA

来源：

BIOLOGICAL CYBERNETICS | 2003年 / 89卷 / 05期

关键词：

D O I：

10.1007/s00422-003-0444-4

中图分类号：

TP3 [计算技术、计算机技术];

学科分类号：

0812 ;

摘要：

A biologically detailed model of the binaural avian nucleus laminaris is constructed, as a two-dimensional array of multicompartment, conductance-based neurons, along tonotopic and interaural time delay (ITD) axes. The model is based primarily on data from chick nucleus laminaris. Typical chick-like parameters perform ITD discrimination up to 2 kHz, and enhancements for barn owl perform ITD discrimination up to 6 kHz. The dendritic length gradient of NL is explained concisely. The response to binaural out-of-phase input is suppressed well below the response to monaural input (without any spontaneous activity on the opposite side), implicating active potassium channels as crucial to good ITD discrimination.

引用

页码：388 / 396

页数：9

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[31] Expanding NEURON's repertoire of mechanisms with NMODL [J].