Factors associated with maintenance of wakefulness test mean sleep latency in patients with mild to moderate obstructive sleep apnoea and normal subjects

被引:31
作者
Banks, S
Barnes, M
Tarquinio, N
Pierce, RJ
Lack, LC
McEvoy, RD
机构
[1] Repatriat Gen Hosp, Adelaide Inst Sleep Hlth, Daw Pk, SA 5041, Australia
[2] Flinders Univ S Australia, Sch Med, Bedford Pk, SA 5042, Australia
[3] Inst Breathing & Sleep, Austin, Australia
[4] Repatriat Med Ctr, Heidelberg, Vic, Australia
[5] Flinders Univ S Australia, Sch Psychol, Bedford Pk, SA 5042, Australia
关键词
Maintenance of Wakefulness Test; Sleepiness and Mild OSA;
D O I
10.1111/j.1365-2869.2003.00383.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This study investigated the possible factors related to the Maintenance of Wakefulness Test (MWT) mean sleep latency. A second analysis explored the characteristics of subjects who had discrepant Epworth Sleepiness Scale (ESS) and MWT scores. A total of 151 subjects (110 mild to moderate obstructive sleep apnoea (OSA) patients and 41 control subjects) were recruited for the study. The subjects completed an overnight Polysomnography (PSG), MWT, cognitive, performance and vigilance tasks and answered self-report questionnaires on mood and sleepiness. A forward stepwise multiple regression was performed on MWT mean sleep latency. The predictor variables age (r = 0.28), subjective sleep history for 1 week prior to MWT (sleep diary; r = 0.19) and number of >4% SaO(2) Dips during the PSG (r = -0.21) best explained the MWT results, but only accounted for 12.8% of the variance in the test. It was found that 33% of subjects had discrepant ESS and MWT scores. A new variable was created to analyse these subjects (MWT/ESS discrepancy score; MED). A forward stepwise multiple regression analysis found that depression, performance errors and sleep disordered breathing explained 13.4% of the variance in MED scores. The MWT is a complex behavioural test whose scores do not seem to have a very robust relationship with potential predictors and co-correlates. Further comprehensive study is needed if the test is to be used in a diagnostically meaningful way.
引用
收藏
页码:71 / 78
页数:8
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