Analysis of the requirement for glycoprotein M in herpes simplex virus type 1 morphogenesis

被引:34
作者
Browne, H [1 ]
Bell, S [1 ]
Minson, T [1 ]
机构
[1] Univ Cambridge, Dept Pathol, Div Virol, Cambridge CB2 1QP, England
关键词
D O I
10.1128/JVI.78.2.1039-1041.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A mutant of herpes simplex virus type 1 lacking both glycoprotein M and glycoprotein E was marginally compromised in terms of its in vitro growth characteristics. This finding is in marked contrast to a similar mutant of the related alphaherpesvirus, pseudorabies virus (A. R. Brack, J. M. Dijkstra, H. Granzow, B. G. Klupp, and T. C. Mettenleiter, J. Virol. 73:5364-5372, 1999), and suggests that the glycoprotein requirements for virion assembly may vary among different members of this family of viruses.
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页码:1039 / 1041
页数:3
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