M cells and the pathogenesis of mucosal and systemic infections

被引:133
作者
Siebers, A
Finlay, BB
机构
[1] UNIV BRITISH COLUMBIA,DEPT BIOCHEM & MOLEC BIOL,VANCOUVER,BC V6T 1Z3,CANADA
[2] UNIV BRITISH COLUMBIA,DEPT MICROBIOL & IMMUNOL,VANCOUVER,BC V6T 1Z3,CANADA
[3] MAX PLANCK INST IMMUNBIOL,D-79108 FREIBURG,GERMANY
关键词
D O I
10.1016/0966-842X(96)81501-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
M cells are specialized epithelial cells of mucosal surfaces lining the respiratory and intestinal tracts. They participate in generating mucosal immune protection by sampling and delivering antigens to the underlying lymphoid tissue. A variety of viral, bacterial and protozoal pathogens exploit the M cell transport pathway to breach mucosal barriers and establish local or systemic infections.
引用
收藏
页码:22 / 29
页数:8
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