Cellular organization by self-organization: mechanisms and models for Min protein dynamics

被引:63
作者
Howard, M
Kruse, K
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Math, London SW7 2AZ, England
[2] Max Planck Inst Phys Komplexer Syst, D-01187 Dresden, Germany
关键词
D O I
10.1083/jcb.200411122
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
We use the oscillating Min proteins of Escherichia coli as a prototype system to Illustrate the current state and potential of modeling protein dynamics in space and time. We demonstrate how a theoretical approach has led to striking new insights into the mechanisms of self-organization in bacterial cells and indicate how these ideas may be applicable to more complex structure formation in eukaryotic cells.
引用
收藏
页码:533 / 536
页数:4
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