Lipid Target Achievement Among Patients With Very High and High Cardiovascular Risk in a Lipid Clinic

被引:27
作者
Barkas, Fotios [1 ]
Liberopoulos, Evangelos N. [1 ]
Kostapanos, Michael S. [1 ]
Liamis, George [1 ]
Tziallas, Dimitrios [1 ]
Elisaf, Moses [1 ]
机构
[1] Univ Ioannina, Sch Med, Dept Internal Med, GR-45110 Ioannina, Greece
关键词
dyslipidemia; high risk; treatment target; cardiovascular disease; lipid clinic; low-density lipoprotein cholesterol; guidelines; CORONARY-HEART-DISEASE; DENSITY-LIPOPROTEIN CHOLESTEROL; CHRONIC KIDNEY-DISEASE; GOAL ATTAINMENT; GREEK ATORVASTATIN; EUROPEAN COUNTRIES; METABOLIC SYNDROME; EVALUATION GREACE; STATIN TREATMENT; UNITED-STATES;
D O I
10.1177/0003319714535073
中图分类号
R6 [外科学];
学科分类号
100210 [外科学];
摘要
This was a retrospective study that assessed achievement of lipid-lowering treatment targets in the setting of a University Hospital Lipid Clinic. Low-density lipoprotein cholesterol (LDL-C) goal attainment according to National Cholesterol Education Program-Adult Treatment Panel III (NCEP ATP III) and European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) guidelines was recorded in 1000 consecutive adult patients followed for 3 years (mean 8 years). The LDL-C targets according to the NCEP ATP III were attained by 66% and 86% of patients with very high (n = 477) and high (n = 408) cardiovascular risk, respectively. Fewer patients were within LDL-C goals according to the ESC/EAS guidelines: 25% and 42%. Overall, 92% of the patients were on statins: 67% were on statin monotherapy, while 33% were on combinations with ezetimibe (25%), -3 fatty acids (5%), fibrates (4%), or colesevelam (2%). Even in a specialist lipid clinic, a large proportion of patients are not at goal according to the recent ESC/EAS guidelines.
引用
收藏
页码:346 / 353
页数:8
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