Synthetic studies on concanamycin A: Total synthesis of concanolide A (concanamycin F)

被引：23

作者：

Jyojima, T ^{[1
]}

Miyamoto, N ^{[1
]}

Katohno, M ^{[1
]}

Nakata, M ^{[1
]}

Matsumura, S ^{[1
]}

Toshima, K ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 33期

关键词：

concanolide A; concanamycin F; vacuolar H+-ATPase inhibitor; lactonization; Stille reaction; aldol reaction;

D O I：

10.1016/S0040-4039(98)01234-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantioselective first total synthesis of concanolide A (concananycin F), which is one of a new class of macrolide antibiotics, concanamycins, has been achieved by a highly effective and convergent route. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6007 / 6010

页数：4

共 35 条

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