Sequential sp(2)-sp(2) coupling reactions in polyene macrolide synthesis. A novel approach to macrolactin A

被引：61

作者：

Boyce, RJ ^{[1
]}

Pattenden, G ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 20期

关键词：

D O I：

10.1016/0040-4039(96)00563-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A combination of two intermolecular sp(2)-sp(2) (Stille and Suzuki) coupling reactions, is employed to elaborate the precursor 2, used in an intramolecular Stille sp(2)-sp(2) macrocyclisation leading to the hexaene macrolide system 1 found in the macrolactin family of bio-active marine metabolites. Copyright (C) 1996 Elsevier Science Ltd

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页码：3501 / 3504

页数：4

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