Systems for applied gene control in Saccharomyces cerevisiae

被引：30

作者：

Maya, Douglas ^{[1
]}

Quintero, Maria Jose ^{[1
]}

Munoz-Centeno, Maria de la Cruz ^{[1
]}

Chavez, Sebastian ^{[1
]}

机构：

[1] Univ Seville, Dept Genet, E-41012 Seville, Spain

来源：

BIOTECHNOLOGY LETTERS | 2008年 / 30卷 / 06期

关键词：

basal expression; gene regulation; heterologous protein production; inducible promoter; Saccharomyces cerevisiae;

D O I：

10.1007/s10529-008-9647-z

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Saccharomyces cerevisiae is frequently used in biotechnology, including fermentative processes in food production, heterologous protein production and high throughput developments for biomedicine. Accurate expression of selected genes is essential for all these areas. Systems that can be regulated are particularly useful because they allow controlling the timing and levels of gene expression. We examine here new expression systems that have been described, including improvements of classical ones and new strategies of artificial gene control that have been applied in functional genomics.

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收藏

页码：979 / 987

页数：9

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