An integrated self-assembled nanofluidic system for controlled biological chemistries

被引：129

作者：

Bolinger, Pierre-Yves ^{[1
,2
]}

Stamou, Dimitrios ^{[2
]}

Vogel, Horst ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland

[2] Univ Copenhagen, Bionanotechnol Lab, Dept Neurosci & Pharmacol & Nano Sci Ctr, DK-2100 Copenhagen, Denmark

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 30期

关键词：

biomimetic systems; nanochemistry; nanoreactors; nanotechnology; vesicles;

D O I：

10.1002/anie.200801606

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Consecutive enzymatic reactions are executed by mixing attoliter volumes (released from nanometer-sized lipid vesicles) in a closed femtoliter reactor vessel (a larger unilamellar vesicle), thus controlling the number of reactants with single-molecule precision. The autonomous nanoreactors need no external interfacing such as outlets or inlets, allowing for extreme miniaturization. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5544 / 5549

页数：6

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