Circadian rhythms - New cogwheels in the clockworks

被引：27

作者：

Schibler, U ^{[1
]}

机构：

[1] Univ Geneva, Dept Biol Mol, CH-1211 Geneva 4, Switzerland

来源：

NATURE | 1998年 / 393卷 / 6686期

关键词：

D O I：

10.1038/31337

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The emerging picture of how autonomous circadian clocks are regulated has been built up from studies in a number of organisms. Four papers now report the identification of one mouse protein — calledClock — in the fruitfly Drosophila melanogaster. Moreover the researchers concerned have found that, in both mice and flies, Clockacts as a heterodimer with a protein dubbed Cycle, and that the two together activate the transcription of the per and tim genes.

引用

页码：620 / 621

页数：2

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