Postantibiotic, postantibiotic sub-MIC, and subinhibitory effects of PGE-9509924, ciprofloxacin, and levofloxacin

被引：13

作者：

Odenholt, I ^{[1
]}

Löwdin, E ^{[1
]}

Cars, O ^{[1
]}

机构：

[1] Univ Uppsala Hosp, Dept Infect Dis & Clin Microbiol, Antibiot Res Unit, Uppsala, Sweden

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 10期

关键词：

D O I：

10.1128/AAC.47.10.3352-3356.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

Postantibiotic effects (PAEs), postantibiotic sub-MIC effects, and sub-MIC effects of the new nonfluoroquinolone PGE-9509924, ciprofloxacin, and levofloxacin against gram-positive and gram-negative strains were investigated. In comparison to ciprofloxacin and levofloxacin, PGE-9509924 exerted very similar PAEs against all strains except for both strains of Streptococcus pneumoniae, where longer PAEs were found for PGE-9509924. All three investigated quinolones showed no minimal PAEs against Pseudomonas aeruginosa.

引用

页码：3352 / 3356

页数：5

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