AStream: an R package for annotating LC/MS metabolomic data

被引：42

作者：

Alonso, Arnald ^{[1
]}

Julia, Antonio ^{[1
]}

Beltran, Antoni ^{[2
,3
]}

Vinaixa, Maria ^{[2
,3
]}

Diaz, Marta ^{[3
,4
]}

Ibanez, Lourdes ^{[3
,4
]}

Correig, Xavier ^{[2
,3
]}

Marsal, Sara ^{[1
]}

机构：

[1] Univ Autonoma Barcelona, Inst Recerca Hosp Univ Vall Hebron, Grp Recerca Reumatol, E-08193 Barcelona, Spain

[2] URV IISPV, Tarragona, Spain

[3] CIBER Diabet & Enfermedades Metab Asociadas, CIBERDEM, Barcelona, Spain

[4] Hosp St Joan de Deu UB, Endocrinol Unit, Barcelona, Spain

来源：

BIOINFORMATICS | 2011年 / 27卷 / 09期

关键词：

D O I：

10.1093/bioinformatics/btr138

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

AStream, an R-statistical software package for the curation and identification of feature peaks extracted from liquid chromatography mass spectrometry (LC/MS) metabolomics data, is described. AStream detects isotopic, fragment and adduct patterns by identifying feature pairs that fulfill expected relational patterns. Data reduction by AStream allows compounds to be identified reliably and subsequently linked to metabolite databases. AStream provides researchers with a fast, reliable tool for summarizing metabolomic data, notably reducing curation time and increasing consistency of results.

引用

页码：1339 / 1340

页数：2

共 4 条

[1] Metabolomics: A global biochemical approach to drug response and disease [J].