Translating developmental time across mammalian species

被引:949
作者
Clancy, B [1 ]
Darlington, RB [1 ]
Finlay, BL [1 ]
机构
[1] Cornell Univ, Dept Psychol, Ithaca, NY 14853 USA
关键词
axonal outgrowth; comparative development; cross-species development; humans; maturational timetables; neurogenesis;
D O I
10.1016/S0306-4522(01)00171-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Conservation of the order in which events occur in developing mammalian brains permits use of regression theory to model the timing of neural development. Following a small adjustment to account for a systematic variability in primate cortical and limbic systems, the model is used to generate a 95-event/nine-species matrix that predicts aspects of neurogenesis and axonal outgrowth in the brains of developing mice, hamsters, rats, spiny mice, rabbits, ferrets, cats, monkeys, and humans. Although data are compiled from species in which the timing of birth and the rate of maturation vary widely, the model proves statistically accurate, with practical implications for improving estimation of milestones of neural development, particularly for humans. Using the three-factor model (species, neural events, and primate adjustments), we produce predictions for the timing of 493 neural occurrences in developing mammalian brains that either have not yet been, or cannot be, empirically derived. We also relate the timing of neural events across the nine species in the form of a reference table calibrated to the development of laboratory rats. This 'translation' table will assist in attempts to equate the neurodevelopmental literature across species with either large or small differences in gestation and maturation, and also permit studies done in a variety of mammals to be applied to better understand human development. The comparative data indicate that humans, although conventionally considered an altricial species, are neurally advanced at birth relative to the other species studied. (C) 2001 IBRO. Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:7 / 17
页数:11
相关论文
共 54 条
[21]   DEVELOPMENT OF THE RETINOFUGAL PATHWAY IN BIRDS AND MAMMALS - EVIDENCE FOR A COMMON TIMETABLE [J].
DREHER, B ;
ROBINSON, SR .
BRAIN BEHAVIOR AND EVOLUTION, 1988, 31 (06) :369-390
[22]  
Dunlop SA, 1997, J COMP NEUROL, V384, P26
[23]   LINKED REGULARITIES IN THE DEVELOPMENT AND EVOLUTION OF MAMMALIAN BRAINS [J].
FINLAY, BL ;
DARLINGTON, RB .
SCIENCE, 1995, 268 (5217) :1578-1584
[24]   Patterns of vertebrate neurogenesis and the paths of vertebrate evolution [J].
Finlay, BL ;
Hersman, MN ;
Darlington, RB .
BRAIN BEHAVIOR AND EVOLUTION, 1998, 52 (4-5) :232-242
[25]   DEVELOPMENT OF THE PERCEPTION OF INVARIANTS - SUBSTANCE AND SHAPE [J].
GIBSON, EJ ;
OWSLEY, CJ ;
WALKER, A ;
MEGAWNYCE, J .
PERCEPTION, 1979, 8 (06) :609-619
[26]   TEMPO OF NEUROGENESIS AND SYNAPTOGENESIS IN THE PRIMATE CINGULATE MESOCORTEX - COMPARISON WITH THE NEOCORTEX [J].
GRANGER, B ;
TEKAIA, F ;
LESOURD, AM ;
RAKIC, P ;
BOURGEOIS, JP .
JOURNAL OF COMPARATIVE NEUROLOGY, 1995, 360 (02) :363-376
[27]  
HEWITT W, 1961, J ANAT, V95, P191
[28]   DEVELOPMENT OF HUMAN AMYGDALA DURING EARLY EMBRYONIC LIFE [J].
HUMPHREY, T .
JOURNAL OF COMPARATIVE NEUROLOGY, 1968, 132 (01) :135-&
[29]  
Huttenlocher PR, 1997, J COMP NEUROL, V387, P167, DOI 10.1002/(SICI)1096-9861(19971020)387:2<167::AID-CNE1>3.0.CO
[30]  
2-Z