Superimposed nanostructured diffraction gratings as high capacity barcodes for biological and chemical applications

被引：11

作者：

Birtwell, S. W. ^{[1
,3
]}

Galitonov, G. S. ^{[1
]}

Morgan, H. ^{[2
]}

Zheludev, N. I. ^{[1
]}

机构：

[1] Univ Southampton, Optoelect Res Ctr, Southampton SO17 1BJ, Hants, England

[2] Univ Southampton, Sch Elect & Comp Sci, Southampton SO17 1BJ, Hants, England

[3] Univ Southampton, Sch Phys & Astron, Southampton SO17 1BJ, Hants, England

来源：

OPTICS COMMUNICATIONS | 2008年 / 281卷 / 07期

基金：

英国工程与自然科学研究理事会;

关键词：

diffraction gratings; optical barcodes; biological applications; combinatorial chemistry;

D O I：

10.1016/j.optcom.2007.04.066

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We describe a new non-contact high capacity optical tagging technique for bead based assays, based on the use of nanostructured barcodes. The tags are generated from a number of superimposed diffraction gratings. With one-dimensional diffraction, capacity for up to 68,000 distinguishable tags has been demonstrated, with a theoretical capacity of up to 10(9) tags. Extension into two dimensions increases this theoretical limit to 10(21) tags. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：1789 / 1795

页数：7

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