Ruthenium catalyzed asymmetric hydrogenation of α- and β-keto esters in ionic liquids using chiral P-Phos ligand

被引：27

作者：

Lam, KH

Xu, LJ

Feng, LC

Ruan, JW

Fan, QH

Chan, ASC ^{[1
]}

机构：

[1] Hong Kong Polytech Univ, Inst Mol Technol Drug Discovery & Synth, Open Lab Chirotechnol, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

[3] Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China

来源：

CANADIAN JOURNAL OF CHEMISTRY | 2005年 / 83卷 / 6-7期

关键词：

ruthenium; asymmetric hydrogenation; keto ester; ionic liquids; P-Phos;

D O I：

10.1139/V05-102

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral dipyridylphosphine ligand P-Phos was used in the Ru catalyzed asymmetric hydrogenation of alpha- and beta-keto esters in room temperature ionic liquids (RTILs) with high conversions and good to excellent enantioselectivities. The catalyst was recycled by simple extraction and reused five times without loss of activity and enantioselectivity.

引用

页码：903 / 908

页数：6

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