Solution solution: using NMR models for molecular replacement

被引：15

作者：

Chen, YW

机构：

[1] Univ Cambridge, Chem Lab, Cambridge CB2 2QH, England

[2] MRC Ctr, Ctr Prot Engn, Cambridge CB2 2QH, England

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2001年 / 57卷

关键词：

D O I：

10.1107/S0907444901010824

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

NMR structures can serve as a good source of search models in crystal structure determination by molecular replacement. However, owing to the inherent problems of NMR models, this procedure is not always straightforward. Here, an updated overview is presented with particular emphasis on the preparation of NMR search models and the latest trends in methodology. An experimental protocol developed recently is described and results on its use in solving a new structure as well as its test against a difficult published case are presented.

引用

收藏

页码：1457 / 1461

页数：5

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