Analysis of molecular interactions in poly(methacrylic acid-g-ethylene glycol) hydrogels

被引：61

作者：

Kim, B

Peppas, NA ^{[1
]}

机构：

[1] Univ Texas, Dept Chem Engn, Austin, TX 78712 USA

[2] Univ Texas, Dept Biomed Engn, Austin, TX 78712 USA

[3] Univ Texas, Dept Pharmaceut, Austin, TX 78712 USA

[4] Purdue Univ, Sch Chem Engn, Biomat & Drug Delivery Labs, W Lafayette, IN 47907 USA

来源：

POLYMER | 2003年 / 44卷 / 13期

关键词：

polymer complexes; ATR-FRIR spectroscopy; pH-sensitive;

D O I：

10.1016/S0032-3861(03)00307-0

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Molecular and structural changes of the P(MAA-g-EG) hydrogels were investigated in their hydrated state using attenuated total reflectance Fourier transform infrared spectroscopy. FUR studies identified the formation of hydrogen-bonded complexes at low pH and polyelectrolyte complexes at high pH. Hydrogen bonding and electrostatic repulsion were not affected by the grafted PEG molecular weight in the hydrogels. Additionally, investigation of the macroscopic swelling properties showed that the presence of the grafted PEG chain in the P(MAA-g-EG) hydrogels contributed to the formation of hydrogen bonds. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：3701 / 3707

页数：7

共 39 条

[21] Solute transport analysis in pH-responsive, complexing hydrogels of poly(methacrylic acid-g-ethylene glycol) [J].