Molecular analysis of Clostridium difficile strains isolated from 18 cases of recurrent Clostridium difficile-associated diarrhea

被引：49

作者：

Tang-Feldman, Y ^{[1
]}

Mayo, S ^{[1
]}

Silva, J ^{[1
]}

Cohen, SH ^{[1
]}

机构：

[1] Univ Calif Davis, Med Ctr, Dept Internal Med, Div Infect Dis & Immunol, Sacramento, CA 95817 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 07期

关键词：

D O I：

10.1128/JCM.41.7.3413-3414.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Recurrence of Clostridium difficile-associated diarrhea (CDAD) occurs in 15 to 20% of patients after discontinuation of treatment. Arbitrarily primed PCR was used to investigate the epidemiology of recurrent CDAD in 18 patients. Reinfection with a new strain occurred in 6 of 18 patients (33.3%), while 12 patients relapsed with the original strain shortly after discontinuation of treatment. These data suggest that reinfection with exogenous C. difficile is a common problem and that not all recurrences are due to relapse.

引用

页码：3413 / 3414

页数：2

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