Macular pigment, photopigments, and melanin: Distributions in young subjects determined by four-wavelength reflectometry

被引:39
作者
Bone, Richard A. [1 ]
Brener, Betty [1 ]
Gibert, Jorge C. [1 ]
机构
[1] Florida Int Univ, Dept Phys, Miami, FL 33199 USA
关键词
macular pigment; reflectometry; retinal camera; lutein; zeaxanthin;
D O I
10.1016/j.visres.2007.09.002
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We have developed an objective procedure, using a modified retinal camera, to determine macular pigment (MP) optical density distributions in the human retina. Using two multi-band filters, reflectance maps of the retinas of young subjects (<25 years old) were obtained at 460, 528, 610 and 670 nm, without pupil dilation. The log-transformed maps were combined linearly to yield optical density maps of MP, cone and rod photopigments, and melanin. MP optical density and heterochromatic flicker photometry results for 22 subjects were in reasonable agreement. Cone photopigments, like MP, showed similar, well-defined peaks at the fovea, whereas rod photopigment showed a minimum. Melanin was more broadly distributed. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3259 / 3268
页数:10
相关论文
共 60 条
[51]   SPECTRAL REFLECTANCE OF THE HUMAN-EYE [J].
VANNORREN, D ;
TIEMEIJER, LF .
VISION RESEARCH, 1986, 26 (02) :313-320
[52]   DERIVATION OF FOVEAL RECEPTOR PRIMARIES [J].
VOS, JJ ;
WALRAVEN, PL .
VISION RESEARCH, 1971, 11 (08) :799-&
[53]   RELATION BETWEEN DIRECTIONAL SENSITIVITY AND SPECTRAL RESPONSE CURVES IN HUMAN CONE VISION [J].
WALRAVEN, PL ;
BOUMAN, MA .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA, 1960, 50 (08) :780-784
[54]  
WEITER JJ, 1986, INVEST OPHTH VIS SCI, V27, P145
[55]   Senescence of foveal and parafoveal cone sensitivities and their relations to macular pigment density [J].
Werner, JS ;
Bieber, ML ;
Schefrin, BE .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2000, 17 (11) :1918-1932
[56]   INFLUENCE OF OCULAR LIGHT SCATTER ON THE EYES OPTICAL-PERFORMANCE [J].
WESTHEIMER, G ;
LIANG, JZ .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1995, 12 (07) :1417-1424
[57]   Spectral absorbance and spatial distribution of macular pigment using heterochromatic flicker photometry [J].
Wooten, BR ;
Hammond, BR .
OPTOMETRY AND VISION SCIENCE, 2005, 82 (05) :378-386
[58]  
Wooten BR, 1999, INVEST OPHTH VIS SCI, V40, P2481
[59]   Macular pigment density in healthy subjects quantified with a modified confocal scanning laser ophthalmoscope [J].
Wüstemeyer, H ;
Moessner, A ;
Jahn, C ;
Wolf, S .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2003, 241 (08) :647-651
[60]   A new instrument for the quantification of macular pigment density:: first results in patients with AMD and healthy subjects [J].
Wüstemeyer, H ;
Jahn, C ;
Nestler, A ;
Barth, T ;
Wolf, S .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2002, 240 (08) :666-671