Photo-induced proton gradients and ATP biosynthesis produced by vesicles encapsulated in a silica matrix

被引:123
作者
Luo, TJM [1 ]
Soong, R
Lan, E
Dunn, B
Montemagno, C
机构
[1] Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
基金
美国国家科学基金会;
关键词
D O I
10.1038/nmat1322
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A liposome/sol-gel architecture in which the liposome provides membrane structure and protein orientation of two transmembrane proteins, bacteriorhodopsin (bR) and F0F1-ATP synthase is studied. The liposome/sol-gel architecture enables to generate photo-induced ion fluxes, quantitatively measurable proton gradients and to produce ATP. The two different proteoliposome-doped gels whose properties are determined by the transmembrane proteins are also investigated. It is found that the materials based on the liposome/sol-gel architecture are able to harness the properties of transmembrane proteins and enables a variety of applications, from power generation and energy storage to the powering of molecular motors.
引用
收藏
页码:220 / 224
页数:5
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