The semi-pinacol rearrangement of homochiral epoxyalcohols catalysed by rare earth triflates

被引：14

作者：

Bickley, JF

Hauer, B

Pena, PCA

Roberts, SM ^{[1
]}

Skidmore, J

机构：

[1] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

[2] BASF AG, ZHF B9, D-67056 Ludwigshafen, Germany

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 11期

关键词：

D O I：

10.1039/b101838h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha,beta -Epoxy ketones, prepared using the polyleucine catalysed asymmetric epoxidation of enones, can be converted into alpha -substituted beta -hydroxy ketones via carbonyl alkylation with Grignard reagents followed by ytterbium triflate catalysed semi-pinacol rearrangement of the resulting epoxyalcohols.

引用

页码：1253 / 1255

页数：3

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