Solving challenging bioorganic problems by exciton coupled CD

被引：24

作者：

Berova, N ^{[1
]}

Borhan, B ^{[1
]}

Dong, JG ^{[1
]}

Guo, JS ^{[1
]}

Huang, XF ^{[1
]}

Karnaukhova, E ^{[1
]}

Kawamura, A ^{[1
]}

Leu, JH ^{[1
]}

Matile, S ^{[1
]}

Nakanishi, K ^{[1
]}

Rickman, B ^{[1
]}

Su, J ^{[1
]}

Tan, Q ^{[1
]}

Zanze, I ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem, New York, NY 10027 USA

来源：

PURE AND APPLIED CHEMISTRY | 1998年 / 70卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1351/pac199870020377

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Determination of molecular chirality is becoming increasingly important due to the sophistication in mode of action studies of biological reactions and the importance of chiral drugs. The exciton coupled CD, based on through space coupling, is a versatile microscale method with superb sensitivity that can be applied to a variety of problems including biopolymers and clusters in lipids. Applications of the exciton coupled CD method to the following problems exemplify its versatility.

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收藏

页码：377 / 383

页数：7

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