Catalytic mechanism and regulation of mammalian adenylyl cyclases

被引：164

作者：

Tang, WJ

Hurley, JH

机构：

[1] Univ Chicago, Dept Pharmacol & Physiol Sci, Chicago, IL 60637 USA

[2] NIDDKD, Mol Biol Lab, NIH, Bethesda, MD 20892 USA

来源：

MOLECULAR PHARMACOLOGY | 1998年 / 54卷 / 02期

关键词：

D O I：

10.1124/mol.54.2.231

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：231 / 240

页数：10

共 77 条

[31] ADENYLYL CYCLASE AMINO-ACID SEQUENCE - POSSIBLE CHANNEL-LIKE OR TRANSPORTER-LIKE STRUCTURE [J].

KRUPINSKI, J ;

COUSSEN, F ;

BAKALYAR, HA ;

TANG, WJ ;

FEINSTEIN, PG ;

ORTH, K ;

SLAUGHTER, C ;

REED, RR ;

GILMAN, AG .

SCIENCE, 1989, 244 (4912) :1558-1564

[32] Protein kinase C inhibits adenylyl cyclase type VI activity during desensitization of the A2a-adenosine receptor-mediated cAMP response [J].

Lai, HL ;

Yang, TH ;

Messing, RO ;

Ching, YH ;

Lin, SC ;

Chern, YJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (08) :4970-4977

[33] STRUCTURAL DETERMINANTS FOR ACTIVATION OF THE ALPHA-SUBUNIT OF A HETEROTRIMERIC G-PROTEIN [J].

LAMBRIGHT, DG ;

NOEL, JP ;

HAMM, HE ;

SIGLER, PB .

NATURE, 1994, 369 (6482) :621-628

[34] FORSKOLIN - A SPECIFIC STIMULATOR OF ADENYLYL CYCLASE OR A DITERPENE WITH MULTIPLE SITES OF ACTION [J].

LAURENZA, A ;

SUTKOWSKI, EM ;

SEAMON, KB .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1989, 10 (11) :442-447

[35] IDENTIFICATION OF FUNCTIONAL DOMAINS OF ADENYLYL-CYCLASE USING IN-VIVO CHIMERAS [J].

LEVIN, LR ;

REED, RR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (13) :7573-7579

[36] LIPID MODIFICATIONS OF G-PROTEINS - ALPHA-SUBUNITS ARE PALMITOYLATED [J].

LINDER, ME ;

MIDDLETON, P ;

HEPLER, JR ;

TAUSSIG, R ;

GILMAN, AG ;

MUMBY, SM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (08) :3675-3679

[37] Catalytic mechanism of the adenylyl and guanylyl cyclases: Modeling and mutational analysis [J].

Liu, Y ;

Ruoho, AE ;

Rao, VD ;

Hurley, JH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (25) :13414-13419

[38]

NEER EJ, 1984, J BIOL CHEM, V259, P4222

[39] LOWERED RESPONSIVENESS OF THE CATALYST OF ADENYLYL CYCLASE TO STIMULATION BY G(S) IN HETEROLOGOUS DESENSITIZATION - A ROLE FOR ADENOSINE 3',5'-MONOPHOSPHATE-DEPENDENT PHOSPHORYLATION [J].

PREMONT, RT ;

JACOBOWITZ, O ;

IYENGAR, R .

ENDOCRINOLOGY, 1992, 131 (06) :2774-2784

[40] Forskolin carbamates: Binding and activation studies with type I adenylyl cyclase [J].

Robbins, JD ;

Boring, DL ;

Tang, WJ ;

Shank, R ;

Seamon, KB .

JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (14) :2745-2752

← 1 2 3 4 5 6 7 8 →