Dimethyl phosphite mediated hydrogen atom abstraction:: A tin-free procedure for the preparation of cyclopentane derivatives

被引：35

作者：

Beaufils, F ^{[1
]}

Dénès, F ^{[1
]}

Renaud, P ^{[1
]}

机构：

[1] Univ Bern, Dept Chem & Biochem, CH-3000 Bern, Switzerland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 33期

关键词：

alkynes; cyclopentanes; fused-ring systems; hydrogen transfer; radical reactions;

D O I：

10.1002/anie.200501309

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A radical transformation! An efficient radical cascade reaction leads to functionalized five-membered rings. Alkenyl radicals are generated from readily available terminal alkynes and a dialkyl phosphite. This tin-free procedure can be run under one-pot conditions (no slow addition), is high yielding, and can be applied to the assembly of fused bicyclic compounds (see scheme). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5273 / 5275

页数：3

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