OUTBREAK OF VIM-1-CARBAPENEMASE-PRODUCING ENTEROBACTER CLOACAE IN A PEDIATRIC INTENSIVE CARE UNIT

被引：36

作者：

Oteo, Jesus ^{[1
]}

Luis Hernandez-Almaraz, Jose ^{[2
]}

Gil-Anton, Javier ^{[3
]}

Vindel, Ana ^{[1
]}

Fernandez, Sara ^{[1
]}

Bautista, Veronica ^{[1
]}

Campos, Jose ^{[1
,4
]}

机构：

[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Bacteriol Serv, Madrid 28220, Spain

[2] Hosp Cruces, Dept Microbiol, Baracaldo, Vizcaya, Spain

[3] PICU Hosp Cruces, Baracaldo, Vizcaya, Spain

[4] Consejo Super Invest Cient, Madrid, Spain

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2010年 / 29卷 / 12期

关键词：

metallo-beta-lactamases; enterobacteria; VIM-1; outbreak; METALLO-BETA-LACTAMASES; PLASMIDS;

D O I：

10.1097/INF.0b013e3181efaa2d

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Pediatric patients are rarely infected with metallo-beta-lactamase-producing Enterobacteriaceae. We describe 3 cases of children infected with VIM-1-producing clonal Enterobacter cloacae. Patients were treated with amikacin and cotrimoxazole. The bla(VIM-1) gene was carried into a class 1 integron and an IncHI2 incompatibility group plasmid. Emergence of pediatric infections caused by carbapenemases-producing Enterobacteriaceae is a critical issue as they are resistant to most beta-lactam antibiotics.

引用

页码：1144 / 1146

页数：3

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