Laser light scattering immunoassay: An improved data analysis by CONTIN method

被引：19

作者：

Antony, T ^{[1
]}

Saxena, A ^{[1
]}

Roy, KB ^{[1
]}

Bohidar, HB ^{[1
]}

机构：

[1] Jawaharlal Nehru Univ, Sch Phys Sci, Ctr Biotechnol, New Delhi 110067, India

来源：

JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS | 1998年 / 36卷 / 2-3期

关键词：

laser light scattering immunoassay; malaria; CONTIN;

D O I：

10.1016/S0165-022X(97)00047-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Laser light scattering immunoassay (LIA) is a diagnostic method for the detection of antibody by monitoring the agglutination of antigen carrier particles mediated by antibody, using dynamic light scattering (DLS) as probe. We have used this method for the detection of antibody to P. falciparum that cause malaria. The data were analysed using CONTIN method and the superiority of the distribution analysis over the conventional interpretation of the data in terms of mean diffusion coefficient or hydrodynamic radius is discussed in detail. (C) 1998 Elsevier Science BN. All rights reserved.

引用

页码：75 / 85

页数：11

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