Enantioselective epoxidation of α,β-enones promoted by α,α-diphenyl-L-prolinol as bifunctional organocatalyst

被引：121

作者：

Lattanzi, A ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Chim, I-84081 Baronissi, Italy

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 13期

关键词：

D O I：

10.1021/ol050694m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An operationally simple and mild protocol for the catalytic enantioselective epoxiclation of alpha,beta-unsaturated ketones has been estabilished using commercially available a,a-diphenyl-L-prolinol as bifunctional organocatalyst and tert-butyl hydroperoxide (TBHP) as oxidant. The epoxides have been obtained in good yields and with up to 80% ee.

引用

页码：2579 / 2582

页数：4

共 48 条

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