Iodine-catalyzed highly efficient Michael reaction of indoles under solvent-free condition

被引:185
作者
Banik, BK [1 ]
Fernandez, M [1 ]
Alvarez, C [1 ]
机构
[1] Univ Texas Pan Amer, Dept Chem, Edinburg, TX 78541 USA
关键词
D O I
10.1016/j.tetlet.2005.02.044
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Michael reaction of indoles with unsaturated ketones has been accomplished in the presence of catalytic amount of iodine under solvent-free condition. (c) 2005 Published by Elsevier Ltd.
引用
收藏
页码:2479 / 2482
页数:4
相关论文
共 34 条
[1]  
[Anonymous], INDOLES
[2]   Sequential one-pot InBr3-catalyzed 1,4-then 1,2-nucleophilic addition to enones [J].
Bandini, M ;
Cozzi, PG ;
Giacomini, M ;
Melchiorre, P ;
Selva, S ;
Umani-Ronchi, A .
JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (11) :3700-3704
[3]   STUDIES ON LACTAMS .96. STEREOSPECIFIC GLYCOSYLATION VIA FERRIER REARRANGEMENT FOR OPTICAL RESOLUTION [J].
BANIK, BK ;
MANHAS, MS ;
BOSE, AK .
JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (17) :4714-4716
[4]   Synthesis of anticancer β-lactams:: mechanism of action [J].
Banik, BK ;
Becker, FF ;
Banik, I .
BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (10) :2523-2528
[5]   Simple synthesis of substituted pyrroles [J].
Banik, BK ;
Samajdar, S ;
Banik, I .
JOURNAL OF ORGANIC CHEMISTRY, 2004, 69 (01) :213-216
[6]   Synthesis, electrophilic substitution and structure-activity relationship studies of polycyclic aromatic compounds towards the development of anticancer agents [J].
Banik, BK ;
Becker, FF .
CURRENT MEDICINAL CHEMISTRY, 2001, 8 (12) :1513-1533
[7]   Polycyclic aromatic compounds as anticancer agents: Structure-activity relationships of chrysene and pyrene derivatives [J].
Banik, BK ;
Becker, FF .
BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (03) :593-605
[8]  
Banik BK, 1997, HETEROCYCLES, V46, P173
[9]   Enantiopure alpha-hydroxy-beta-lactams via stereoselective glycosylation [J].
Banik, BK ;
Manhas, MS ;
Bose, AK .
TETRAHEDRON LETTERS, 1997, 38 (29) :5077-5080
[10]   Stereoselective synthesis of β-lactams with polyaromatic imines:: Entry to new and novel anticancer agents [J].
Banik, I ;
Becker, FF ;
Banik, BK .
JOURNAL OF MEDICINAL CHEMISTRY, 2003, 46 (01) :12-15