Depression Following Open-Heart Surgery: A Path Model Involving Interleukin-6, Spiritual Struggle, and Hope Under Preoperative Distress

被引：21

作者：

Ai, Amy L. ^{[1
]}

Pargament, Kenneth I. ^{[2
]}

Appel, Hoa B.

Kronfol, Ziad ^{[3
]}

机构：

[1] Univ Pittsburgh, Pittsburgh, PA 15260 USA

[2] Bowling Green State Univ, Bowling Green, OH 43403 USA

[3] Weill Cornell Med Coll, New York, NY USA

来源：

JOURNAL OF CLINICAL PSYCHOLOGY | 2010年 / 66卷 / 10期

关键词：

depression; interleukin-6 (IL-6); spiritual struggle; avoidant coping; hope; anxiety; existential distress; cardiac disease; open heart surgery; CORONARY-ARTERY-DISEASE; BYPASS GRAFT-SURGERY; CARDIOVASCULAR-DISEASE; MAJOR DEPRESSION; RELIGIOUS INVOLVEMENT; PLASMA INTERLEUKIN-6; PSYCHOLOGICAL STRESS; PSYCHOSOCIAL FACTORS; CARDIAC-SURGERY; MENTAL STRESS;

D O I：

10.1002/jclp.20716

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Faith factors (i.e., factors pertaining to religion/spirituality) have been linked with well-being and adequate coping. Few studies have investigated negative aspects of religious coping, such as spiritual struggle. Based on the multidisciplinary literature and on previous findings, the study's analysis estimated parallel psychophysiological pathways from preoperative distress to postoperative depression in patients undergoing open heart surgery. Plasma samples for interleukin(IL)-6 were obtained before surgery. The results showed that a link between spiritual struggle and IL-6 mediated the indirect effects of preoperative anxiety on postoperative depression. Avoidant coping also mediated the influence of anxiety on postoperative maladjustment. Further, hope played a protective mediating role to moderate the undesirable influences of the spiritual struggle-IL-6 link and maladaptive coping on postoperative mental health attributes. (C) 2010 Wiley Periodicals, Inc. J Clin Psychol 66:1057-1075, 2010.

引用

页码：1057 / 1075

页数：19

共 98 条

[71] Depression and anxiety and outcomes of coronary artery bypass surgery [J].