Search for mitochondrial DNA mutations in migraine subgroups

被引：28

作者：

Haan, J

Terwindt, GM

Maassen, JA

't Hart, LM

Frants, RR

Ferrari, MD

机构：

[1] Leiden Univ, Med Ctr, Dept Neurol, NL-2300 RC Leiden, Netherlands

[2] Rijnland Hosp, Dept Neurol, Leiderdorp, Netherlands

[3] Leiden Univ, Med Ctr, Dept Med Biochem, NL-2300 RC Leiden, Netherlands

[4] Leiden Univ, Med Ctr, Dept Human Genet, NL-2300 RC Leiden, Netherlands

来源：

CEPHALALGIA | 1999年 / 19卷 / 01期

关键词：

MELAS; migraine; mitochondria; mtDNA mutations;

D O I：

10.1046/j.1468-2982.1999.1901020.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

It has been suggested that mitochondrial mutations cause migraine(-like) symptoms. The presence of mtDNA mutations (3243, 3271, 11084, and deletions) was investigated in three migraine subgroups (maternally transmitted migraine with and without aura, migrainous infarction, and nonfamilial hemiplegic migraine). No mutations were found. These mutations and deletions probably are not involved in the migraine subgroups studied, although an investigation of other material (e.g., muscle tissue) would have shown this with more certainty.

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收藏

页码：20 / 22

页数：3

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