Great ape DNA sequences reveal a reduced diversity and an expansion in humans

被引：145

作者：

Kaessmann, H ^{[1
]}

Wiebe, V ^{[1
]}

Weiss, G ^{[1
]}

Pääbo, S ^{[1
]}

机构：

[1] Max Planck Inst Evolut Anthropol, Leipzig, Germany

来源：

NATURE GENETICS | 2001年 / 27卷 / 02期

关键词：

D O I：

10.1038/84773

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The extent of DNA sequence Variation of chimpanzees is several-fold greater than that of humans'. It is unclear, however, if humans or chimpanzees are exceptional among primates in having low and high amounts of DNA sequence diversity, respectively. To address this, we have determined approximately 10,000 bp of noncoding DNA sequences at Xq13.3 (which has been extensively studied in both humans and chimpanzees(1,2)) from 10 western lowland gorillas (Gorilla gorilla gorilla) and 1 mountain gorilla (Gorilla gorilla beringei; that is, from 2 of the 3 currently recognized gorilla subspecies'), as well as 8 Bornean (Pongo pygmaeus pygmaeus) and 6 Sumatran (Pongo pygmaeus abelii) orang-utans. representing both currently recognized orangutan subspecies(4). We show that humans differ from the great apes in having a low level of genetic Variation and a signal of population expansion.

引用

页码：155 / 156

页数：2

共 23 条

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