Molecularly imprinted TiO2 thin film by liquid phase deposition for the determination of L-glutamic acid

被引：58

作者：

Feng, LA

Liu, YJ

Hu, JM ^{[1
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

[2] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China

来源：

LANGMUIR | 2004年 / 20卷 / 05期

关键词：

D O I：

10.1021/la0357108

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

For the first time, the feasibility of a molecularly imprinted liquid phase deposition (LPD) thin film has been demonstrated. Thin films of titanium oxide imprinted with L-glutamic acid were prepared by the LPD method on a gold-coated quartz crystal microbalance. The imprinted molecule could be removed upon treatment with immersion in deionized water. A sensor was developed on the basis of this method and showed good sensitivity, selectivity, and reproducibility to the template molecule. An equation was deduced to characterize the interaction between molecularly imprinted films and the template by virtue of Scatchard analysis. X-ray photoelectron spectroscopy was introduced to show the evidence for the molecular imprinting phenomenon. The linear relationship between the frequency shifts and the concentration of analyte in the range of 10-200 muM was obtained. LPD proves to be a powerful method for imprinting titanium oxide thin films.

引用

页码：1786 / 1790

页数：5

共 30 条

[1] Study of the nature of recognition in molecularly imprinted polymers, II [1] - Influence of monomer-template ratio and sample load on retention and selectivity [J].