Influence of visceral and subcutaneous fat in bone mineral density of obese adolescents

被引：28

作者：

Campos, Raquel M. S. ^{[1
]}

Lazaretti-Castro, Marise ^{[2
]}

de Mello, Marco Tulio ^{[3
]}

Tock, Lian ^{[1
]}

Silva, Patricia L. ^{[1
]}

Corgosinho, Flavia C. ^{[1
]}

Carnier, June ^{[1
]}

de Piano, Aline ^{[1
]}

Sanches, Priscila L. ^{[1
]}

Masquio, Deborah C. L. ^{[4
]}

Tufik, Sergio ^{[3
]}

Damaso, Ana R. ^{[1
,4
,5
]}

机构：

[1] Univ Fed Sao Paulo Unifesp, Grad Studies Program Nutr, Sao Paulo, Brazil

[2] Univ Fed Sao Paulo, Dept Endocrinol, Sao Paulo, Brazil

[3] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo, Brazil

[4] Univ Fed Sao Paulo, Grad Studies Program Interdisciplinary Hlth Sci, Sao Paulo, Brazil

[5] Univ Fed Sao Paulo, Dept Biosci, Sao Paulo, Brazil

来源：

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2012年 / 56卷 / 01期

基金：

巴西圣保罗研究基金会;

关键词：

Adolescent; visceral fat; subcutaneous fat; bone mass; ADIPOSE-TISSUE; ADIPONECTIN; LEPTIN; MASS; ASSOCIATION; PREVALENCE; OVERWEIGHT; HORMONES; WEIGHT; MEDIATORS;

D O I：

10.1590/S0004-27302012000100003

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Objective: To verify the influence of visceral and subcutaneous fat, as well adipokines in bone mineral density (BMD) in obese adolescents. Subjects and methods:The study involved 125 postpubertal obese adolescents (45 boys and 80 girls). Anthropometric measurements, body composition, visceral and subcutaneous fat, and BMD were determined. Leptin, adiponectin, and insulin levels also analyzed. Results: Data demonstrated a negative relationship between BMD with insulin resistance, visceral fat and leptin concentration; and bone mineral content with visceral/subcutaneous ratio. Positive association between BMD and subcutaneous fat was observed. Conclusions: Visceral fat and insulin resistance, as well as visceral/subcutaneous ratio and leptin concentration, were negative predictors of BMD in boys and girls, respectively. However, subcutaneous fat had a protective influence in BMD only in boys. Arq Bras Endocrinol Metab. 2012;56(1):12-8

引用

页码：12 / 18

页数：7

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